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Jiao, C

Phase I study of s-trans, trans-farnesylthiosalicyclic acid (FTS), a novel oral Ras inhibitor, in patients with refractory hematologic malignancies

Step 3 Compound 2 (66 mg) was obtained from compound if (168 mg) and compound 2c (100 mg) according to the method of Example 1

(12) Glutathione plays an important role in toxicology and homeostasis because of its ability to coordinate a variety of metal ions (13, 14), in part due to its cysteine thiol functionality

[DOI] [PubMed] [Google Scholar] 20.Park M.H., Igarashi K

HIV infection induces oxidative stress, which plays an important role in the development of various virus-associated pathologies 111,112,113
