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This is related to the fact that the presence of thiol groups can disrupt disulfide bonds and therefore confine the purification of the target protein (Fong et al., 2010)
doi: 10.1038/nrgastro.2017.88
It is a big difference having a professional doctor in a well-known clinic
doi: 10.1046/j.0022-3042.2002.00774.x
Prog Brain Res 184: 316 [DOI] [PubMed] [Google Scholar] Hauswirth WW, Laipis PJ 1982
A 2019 case report describes a case of a young woman who was treated for severe pernicious anemia with multiple daily doses of 1 milligram (mg) of cyanocobalamin, a synthetic form of B12
