can l carnitine raise blood pressure l-carnitine, a friend or foe for cardiovascular disease? A Mendelian randomization study | BMC Medicine The effects of L-carnitine supplementation

Raju M, Varakumar S, Lakshminarayana R, Krishnakantha TP, Baskaran V

Fatty acids play a critical role in regulating macrophage polarization: saturated fatty acids (e.g., palmitic acid) promote M1 polarization [45, 46], while polyunsaturated fatty acids (e.g., DHA) and n-3 fatty acids (e.g., EPA/DHA) induce M2 polarization [45,46,47]

This may be involved in the regulation of neuroendocrine functions, the immune system, and inflammatory response, as well as play a role in development

doi: 10.17219/acem/186949 13

In triple-negative breast cancer, its inhibitor DMOCPTL induced ferroptosis of cancer cells by the ubiquitination of GPX4 of via regulating the activity of EGR1 [155]

Consistent with this, Dunlevy et al