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Thioredoxin reductase, cytosolic superoxide dismutase, cytosolic catalase, and cytochrome c peroxidase are all encoded by the same set of genes

Chronic HG has been linked to advanced glycation end products AGEs formation, which in turn activates intracellular signaling and promotes the expression of pro-inflammatory transcription factors and the release of various inflammatory cytokines (93)

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Prepulse inhibition and fear-potentiated startle are altered in tissue inhibitor of metalloproteinase-2 (TIMP-2) knockout mice

The relation between intracellular H 2 O 2 concentration and OxyR oxidation levels observed at steady state after addition of H 2 O 2 to the WT (filled squares), trx1 (filled diamonds), or trx3 (filled circles) strains is plotted according to the data shown in Table 1 in the main text

Many such compounds are supported mainly by preclinical findings or small-scale clinical studies of variable quality