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Bevacizumab (10 mg/kg) was administered on days 1 and 15 every 28 days

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Rapamycin treatment decreased the gene expression of MMP-3, MMP-13, IL-1, IL-6, TNF-, and protein levels of P16 and P21 in bleomycin-treated AFSCs suggesting that potential of rapamycin for disc degenerative diseases