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Other treatment regimens as well as prophylactic measures have been explored in the literature and are summarized in the table below

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As the epithelial layer is the main form of the colonic barrier, we inferred that SP might reduce intestinal inflammation and promote the repair of the gut mucosal barrier by inactivating the cGAS-STING pathway in intestinal epithelial cells

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Additionally, endothelium-derived NO inhibits platelet adhesion, leukocyte infiltration, and oxidative stress, thereby contributing to vascular homeostasis 8,9

Previous studies have shown that supplementation of vitamin D prevents acute respiratory tract infections (Martineau et al, 2017)