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The upregulation of Sirt3 protects against impaired electron transport and ATP production, loss of mitochondrial membrane potential (MMP) and neuronal vulnerability, and treatment with Sirt3 agonists can restore mitochondrial integrity, reduce S oligomers and oxidative stress

Hodos et al., 2016)

Commoner B, Townsend J, Pake GE

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Moderate consumption of a soluble green/roasted coffee rich in caffeoylquinic acids reduces cardiovascular risk markers: results from a randomized, cross-over, controlled trial in healthy and hypercholesterolemic subjects

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