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Following randomization, participants entered a six-month treatment period with either 2 g/day of oral L-C or placebo (cellulose), both given in divided doses in the morning (2 500 mg) and evening (2 500 mg)

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The level of plasma Lp-PLA 2 can be positively affected by low-calorie diets associated with weight loss or after drug treatment with the various classes of hypolipidemic drugs discussed below in Pharmacologic Intervention in Hyperlipidemias

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