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doi: 10.1016/j.biomaterials.2019.119342 [DOI] [PMC free article] [PubMed] [Google Scholar] 140.Seino S, Ikehata H, Tanabe M, et al
doi: 10.3390/ijms22094871

Glutathione depletion has been linked to the pathophysiology of idiopathic pulmonary fibrosis [171] adult respiratory distress syndrome [162, 172] bronchopulmonary dysplasia [173] and cystic fibrosis [174]

doi: 10.4103/ijpc.ijpc_69_21 13

Icariin, a flavonoid abundant in the herb Epimedium, ameliorated MCD diet-induced lipid peroxidation, restored mitochondrial structure in the livers of NASH mice, and exerted hepatoprotective effects through the activation of Nrf2, which in turn significantly elevated the protein levels of GPX4 and a cystine/glutamate transporter (xCT) [143]
It is commonly characterized by changes in taste, loss of appetite, and feelings of depression
