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Biosynthetic pathway of free heme The biosynthetic pathway of heme is divided into three modules in microorganisms, including 5-aminolevulinic acid (ALA), uroporphyrinogen (urogen) III, and heme synthetic modules (Fig

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10.1016/j.biopha.2023.114930 23 JiaD.GaoP.LvY.HuangY.ReillyJ.SunK.et al (2022)

Lack of gut microbiota diversity and elevated C-reactive protein, indicative of chronic information, are independent prognostic biomarkers for LC, CFS, and vitamin D deficiency (Moreira-Rosrio et al., 2021)