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doi: 10.3389/fneur.2020.00088 Received 19 September 2019 Accepted 24 January 2020 Published 14 February 2020 Volume 11 - 2020 Edited by Pamela Ann McCombe, University of Queensland, Australia Reviewed by Ester Moral, Hospital of Sant Joan Desp Moiss Broggi, Spain

The production of harmful oxidative products by ROS has led to the initiation and progression of numerous acute and chronic diseases [106]

PLoS ONE 3:e1944 Weiduschat N, Mao X, Hupf J, Armstrong N, Kang G, Lange DJ, Mitsumoto H, Shungu DC (2014) Motor cortex glutathione deficit in ALS measured in vivo with the J-editing technique