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For instance, in a randomized, placebo-controlled trial in healthy adults, subcutaneous CJC-1295 injections produced sustained, dose-dependent increases in GH (two to 10 times) and IGF-1 (1.5 to three times) levels over several days, demonstrating prolonged GH axis stimulation without serious adverse effects, a hormonal milieu associated with anabolic and metabolic effects

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2017, doi: 10.1007/s00109-016-1488-y

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Nature Medicine 2024: s41591-024-03018-2 48-week MRI-PDFF liver fat reduction (51% at 1 mg, 86% at 12 mg)