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Metabolic Effects: Adipose Tissue Regulation and Energy Balance
These findings position the compound as a valuable research tool for investigating whether NNMT modulation influences age-associated metabolic changes in mammalian aging models
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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse diet-induced obesity in mice. Nature Medicine, 25(11), 17611771
In experimental models, research models demonstrate altered insulin sensitivity and glucose handling parameters, with plasma total cholesterol levels showing reductions
