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The review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines [15], with registration in NIHR-PROSPERO (CRD 42024505263)
doi: 10.1177/0163278711424281 [DOI] [PMC free article] [PubMed] [Google Scholar] 55
High proline content (three consecutive prolines at positions 3-5) introduces conformational constraints
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