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This mechanism could theoretically help suppress tumor development by removing cells that might otherwise contribute to a cancer-friendly environment

331 This shift in HIF expression likely underlies the observation that under conditions of prolonged hypoxia the initial protective mechanisms of the kidney either fail to be engaged or are down-regulated

Xu X, Yuan X, Li N, Dewey WL, Li PL, Zhang F

PDX models have been successfully established from all major molecular MB subgroups and have demonstrated stability across multiple passages, although subclonal populations may undergo selection during serial transplantation

-Synuclein phase separation and amyloid aggregation are modulated by C-terminal truncations

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