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AOD9604 vs MOTS-c: MOTS-c is a mitochondria-derived peptide that has shown promise for metabolic health and fat loss through effects on mitochondrial function and insulin sensitivity

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When NNMT is overexpressedas seen in aging and insulin-resistant statesNAD+ levels drop, leading to impaired mitochondrial activity and reduced ATP production

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Nat Rev Immunol 4:583594 Duffield JS, Lupher M, Thannickal VJ, Wynn TA (2013) Host responses in tissue repair and fibrosis

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