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FIGURE 7 Evaluation of the NLRP3 inflammasome inhibition of 4-MESC through Western blot To further investigate the NLRP3 inflammasome suppression by 4-MESC, western blotting was used to examine the expression study of proteins such as NLRP3, Nf-kBp65, caspase 1, and b-actin

After at least one day, the proteome of the cells was analyzed using a 2D gel electrophoresis technique

2013 Sep 15;191(6):3419-29

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doi: 10.3389/fnins.2022.888014 27 Miranda-MoralesEMeierKSandoval-CarrilloASalas-PachecoJVazquez-CardenasPArias-CarrionO

The accumulation of advanced glycation end products (AGEs) can also induce apoptosis (cell death) in fibroblasts, resulting in a significant loss of hyaluronic acid, collagen, and elastin