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TNF- treatment in adipocytes induces the increase in p-IRS-1 (Ser307) and decrease in p-IRS-1 (Tyr612), partly by increasing p-JNK and ERK1/2 [63]
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doi:10.1002/cpt.3110
Specific dosing schedules are not provided here due to safety concerns and variability in response
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This essentiality is due to the inability to insert double bonds at the third and sixth carbon from CH3 end in n-3 and n-6 locations
