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Thus, the thiol group in BSH is more acidic compared to the thiol group in Cys suggesting an enhanced level and reactivity of the BSH thiolate anions to detoxify reactive species

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From the Nobel prize press release: John B Gurdon discovered in 1962 that the specialisation of cells is reversible

At the same time, appetite changes, gastrointestinal symptoms, or impaired absorption may limit oral intakemaking repletion more challenging through diet or supplements alone

doi: 10.1023/A:1018490212481

As such, the kidney is particularly vulnerable to damage caused by oxidative stress