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Veerbeek JM, Langbroek-Amersfoort AC, van Wegen EEH, et al
Furthermore, this integrated approach demonstrated immunomodulatory effects characterized by elevated IL-2 with concurrent reduction in the levels of TGF-, IFN-, and interleukins (IL-23, IL-4, and IL-5), and improved immune function, as evidenced by increased CD4 + and CD4 + /CD8 + ratios [120, 122]

M.PachecoA
2007, 28 (1 Suppl International), S77-100

Review: soluble innate immune pattern-recognition proteins for clearing dying cells and cellular components: implications on exacerbating or resolving inflammation

Cysteine starvation or xCT blockade confers the opposite result and increases cellular NADPH pools