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Meyer C, Stumvoll M, Nadkarni V, Dostou J, Mitrakou A, Gerich J

Vesicular formulations may exhibit a slower drug release rate, which can reduce the concentration gradient across the skin and thereby limit transdermal diffusion, resulting in lower cumulative drug permeation into the receptor medium [58, 63]

Safety must be prioritized over efficacy claims

This wound healing enhancer effect was also supported by Han et al (142) regarding the topical use of 50% N

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