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209 Elevated ROS levels, along with mtDNA polymerase mutations that cause replication errors, contribute to mtDNA mutations, multiple deletions, and reduced copy numbers, all of which accumulate with age, leading to mitochondrial dysfunction and cell death

Vitamin E Vitamin E is an essential nutrient with antioxidant properties and includes both tocopherol (TP) and tocotrienol (T3), differing in their aliphatic tails (80)

In addition to Pgp, BCRP transports some ASDs, such as lamotrigine

The aim of this review is to summarize the state-of-the-art of the n-3 effects on certain conditions caused by alcohol intake, focusing primarily on brain damage and alcoholic liver disease

[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Berg J., Tymoczko J., Stryer L

E., Shalem, O