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These diverse applications require extensive additional research to establish safety and efficacy profiles appropriate for clinical translation, but suggest GHK-Cu's therapeutic potential may extend substantially beyond current dermatological applications, potentially overlapping with emerging applications of other regenerative peptides including cerebrolysin for neurological applications and peptides targeting musculoskeletal regeneration

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In contrast, melatonin therapy demonstrated beneficial outcomes for sleep, cognitive function, depression, and behavioral symptoms in individuals with mild cognitive impairment