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Current investigations continue to assess NNMT-associated enzymatic activity, NAD+-related signaling, and cellular energy metabolism behavior across different in vitro systems and analytical frameworks

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therefore, MAO-driven metabolism of substances such as dopamine, serotonin, norepinephrine, and tyramine normalizes only after new MAO is synthesized, and this process takes about 2 weeks to be complete after the MAOI has been washed out of the body