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270 In addition, a recent study showed that short-chain fatty acids can act as ligands of G-protein-coupled receptors (GPCRs), such as GPR41, GPR43, and GPR109A, to activate PKC that can in turn phosphorylate ZO-1 in order to increase intestinal barrier function

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The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion

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doi: 10.1080/21645515.2021.2002083

In some cases, self-reactive lymphocytes can cause damage to the host [46]