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They act on different pathways

To address this, we analyzed these metabolites in isolated cerebral vessels and in the brain parenchyma over a range of ages in the APOE-TR mouse model

Liver tissue was crushed and prepared with previously described methods to separate the aqueous, lipid, and protein layers, 9 and sent to the Department of Biochemistry at the University of Cambridge, Cambridge, UK, where liquid chromatography mass spectrometry was undertaken

10.1016/j.eururo.2022.05.008 6

Emerging therapeutic strategies aimed at overcoming Nrf2-driven ferroptosis resistance include the use of inhibitors such as triptolide and brusatol, which impair antioxidant defenses and sensitize isocitrate dehydrogenase 1 (IDH1)-mutant gliomas to ferroptotic cell death [69]

10.1080/10408690091189176 [DOI] [PubMed] [Google Scholar] Smolensky, D