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The roles of coenzyme Q in disease: direct and indirect involvement in cellular functions

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It plays a vital role in transporting fatty acids to the mitochondria during the breakdown of fats, ensuring a steady supply of metabolic energy

PGC-1 specifically interacts with PPAR and other members of the nuclear hormone receptors superfamily, such as TR, retinoic acid (RA) receptor and estrogen receptor (ER) to control lipid metabolism in adipose [56], muscle [57], and cancer [58]
