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(7) Centrifuge for 10 min (12000 rpm, 4C), 150 L of supernatant was loaded into an LC-MS injection vial with a liner tube for LC-MS analysis

We applied this assay to analyze whole blood and plasma samples from 11 heathy donors

All ligation reactions were performed using Ligation high Ver

This results in deformation of the posterior fovea of the lamina cribrosa, compressing the axons of RGCs that pass through, which blocks the axoplasmic transport of RGCs, resulting in RGC cell death [5]

Gene therapies to upregulate specific isoforms and biomarkers for early detection are also on the horizon, aiming for personalized interventions