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For optimal absorption, its advised to take these supplements on an empty stomach, ideally in the morning or 2-3 hours after meals

Pharmacokinetic drug-drug interactions with methotrexate in oncology

doi: 10.1002/jcp.28632

Some people may notice stomach discomfort or indigestion, which is another reason the tablets are usually taken after meals

Yes a companion is welcome and recommended for surgical procedures, especially for the trip home and early recovery
Sugar, honey, treacle
