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Description
The synthesis of thromboxane A2 from arachidonic acid, which serves as a precursor to TBXA2, is facilitated by the activation of phospholipase A2 (PLA2) and subsequent conversion by cyclooxygenase 1 (COX-1) (167)

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Cyanocobalamin | Drugs - BNF - NICE

Risk factors include the speed and magnitude of weight loss, pre-existing nutritional deficiencies, age, sex (women are more commonly affected), and individual genetic susceptibility

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Ansley DM, Wang B