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A multiplexed HILIC-MS/HRMS assay for the assessment of transporter Inhibition biomarkers in phase I clinical trials: Isobutyryl-Carnitine as an organic cation transporter (OCT1) biomarker

Natalie Parletta Julia J Rucklidge Symptoms of hyperactivity, impulsivity and inattention, associated with attention deficit hyperactivity disorder (ADHD), can constitute a chronic, often debilitating psychiatric condition

The detergent Tergitol (NP-40, Sigma Aldrich) was added at a concentration of 0.001% to RNAi agar prior to autoclaving for all fatty acid ( cis and trans ) and control supplementation plates

However, this pathway lacks validation through in vitro and animal experiments [110]

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