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The GSTT proteins are generally about 250 amino acids long

The presence of these enzymes in excitatory neurons may suggest that GABA metabolism is not limited to the inhibitory synapse (i.e., inhibitory neurons and associated astrocytes as illustrated in Figure 1), or that GABAT and SSADH could serve alternative cellular functions

Acarbose decreased key markers (Iba1 + microglia, tumor necrosis factor-, and glial fibrillary acidic protein) of hypothalamic inflammation, while long-term treatment of acarbose (from 3 to 9 months, 20 mg/kg/day) enhanced memory during aging in SAMP8 mice [149, 150]

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[88] The incidence and severity of neurological side effects may vary depending on individual patient susceptibility and concurrent medications