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Annual Rev Biophys 42(1):217239 Benoist C, Mathis D (2012) Treg cells, life history, and diversity

-A- D-Nle-Cys-Ile-NH-(CH 2 ) 5 -CONH 2s TM#TM D- Nle-Met-Ile-NH-(CH 2 ) 5 -CONH 2 D-Nle-Trp-Ile-NH-(CH 2 ) 5 - CONH 2 D-Nle-Trp-Ile-NH-(CH 2 ) 5 - CONH 2 FIG 24A and B Inhibition of HGF dimerization by D-Nle-X-IIe-NH-(CH 2 ) 5 -CONH 2 analogs

Biological Activity KLOW exerts its biological effects through coordinated action across cellular repair, inflammation regulation, and oxidative protection pathways
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Together, these peptides restore metabolic balance and regenerate tissue inside and out