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doi: 10.3390/antibiotics12060978 47

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Moreover, a host of additional studies also conclude that vitamin C and/or vitamin E, given intravenously or orally, has little to no effect on the occurrence of cardiovascular events in healthy women 83 and male smokers 84,85

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ROS are important signaling molecules that regulate cellular metabolism, proliferation, and survival [12, 13]

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A prospective, placebo-controlled, randomized, single-blind phase II trial was conducted in a multidisciplinary university hospitals ICU where two groups of patients with systemic inflammatory response syndrome aged more than 18 years were randomized to receive either placebo or intravenous Se as a bolus-loading dosage of 2000 g Se followed by a continuous infusion of 1600 g Se per day for ten days, the study revealed that Se supplementation improved illness severity, and reduces the risk of VAP [90]

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However, this may not restore optimum vision and cataract surgery often may not be readily available, especially in developing countries which lack adequate surgical facilities and qualified eye surgeons

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