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It interferes with the maturation of the NOTCH1 receptor by blocking its S1 cleavage, a crucial step in NOTCH1 activation
Obwohl die Forschung an Tieren durchgefhrt wurde, zeigt Epithalon vielversprechende Ergebnisse fr die Anwendung beim Menschen
Neoplasia 19 , 10221032 (2017)
Molecular interaction studies further revealed that SMOC1 forms stable complexes with A as early as the MCI stage, with binding strength intensifying as the disease progresses [200]
doi: 10.1002/advs.202412311
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