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Overexcitation of the neuron leads to depolarization of the presynaptic membrane, prompting the opening of voltage-gated Ca 2+ channels and allowing a massive influx of Ca 2+ into the presynaptic neuron [13,14,15]

Expression of the activity of cystine/glutamate exchange transporter, system x(c)(-), by xCT and rBAT

This study directly links lactate metabolism to epigenetic modification and finds that accumulated lactate can catalyze the lactylation of histone H3K18, thereby forming an epigenetic-metabolic positive feedback loop that promotes the expression of oncogenes

Lutein prevents cataract development by mitigating photo-oxidative stress [128]

Biochem Mosc 89(11):18891903 Mira RG, Lira M, Tapia-Rojas C, Rebolledo DL, Quintanilla RA, Cerpa W (2020) Effect of alcohol on hippocampal-dependent plasticity and behavior: role of glutamatergic synaptic transmission

Wermeling, D