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Each molecular variant of vitamin B12, derived from food or supplements, is initially reduced in the human body to cobalamin, which is converted into active intracellular forms of vitamin B12 (i.e., MeCbl and AdCbl) during subsequent metabolic processes [17]
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Long-term safety studies extending up to 12 months showed no adverse effects, which is rare for a compound with such potent biological activity
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Very recently HK-1 has also been shown to cause degranulation of the human mast cell line leukocyte adhesion deficiency-2 (LAD2) [110]
