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This observation confirmed that the continuous electron density map between the DEL7 primary amine group and the thiol group of C145 is an oxygen atom bridging a sulfur and nitrogen atom to form the S-O-N entity due to crystallographic artifacts introduced during crystal growth at pH 5-6 16

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doi: 10.1007/s10787-022-01130-8 228 LiuXGuoJWLinXCTuoYHPengWLHeSYet al