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As shown in Table 3, animals were assigned to 4 groups, which were subcutaneously administered GX-G3 at doses of 0 (vehicle control), 1 (T1), 3 (T2), or 10 (T3) mg/kg once a week for 4 weeks
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The retinal pigment epithelium (RPE) performs a number of crucial functions, such as in the formation of an external retinal barrier, transport, retinoid retention, phagocytosis, the degradation of segmental photoreceptors, and protection against light and oxidative stress [25]

Development and use of S1P 2 -selective antagonists may provide a new approach to reduce glutamate neurotoxicity in neurologic diseases
