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Do animal studies translate to humans

Shepherd SJ, Gibson PR

The STEP-1 trial tested the effect of high-dose semaglutide to produce weight loss in people with obesity who do not have diabetes
Patients with chronic kidney disease, reduced kidney function, or other significant medical conditions should always discuss peptide therapy with their healthcare provider before starting treatment
One regulatory note worth holding alongside his framing: the FDA placed several of the peptides he discusses (including BPC-157, CJC-1295, and Ipamorelin) onto a Category 2 list in 2023, citing a lack of safety data rather than reported harms

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