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With respect to the biological pathway, there is consistent evidence for the mitogenic role of IGF1 in carcinogenesis by increasing cell proliferation and inhibiting apoptosis

doi: 10.1016/j.anai.2017.02.014

Mentioned in This Article: Glutathione A powerful antioxidant, glutathione is the first line of defense against oxidative stress
[Google Scholar] 41.Weber F

Finally, it was recently suggested that IGF-I has significant characteristics to be a good marker for the insulin resistance syndrome and risk of cardiovascular disease, since logistic regression analysis showed that each unit increase in log-transformed IGF-I concentrations was associated with a 90.5% reduction in the risk of metabolic syndrome [274]

[2] Pizzorno, J
