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Under stress conditions, PINK1 promotes Parkin recruitment to the OMM to ubiquitinate mitochondrial proteins and polyubiquitin chains are subsequently phosphorylated by PINK1 as an initiation signal for autophagy
Garbern JY, Neumann M, Trojanowski JQ, Lee VM, Feldman G, Norris JW, et al
Results in animal studies In rodent experiments led by Dr
