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Methylated B vitamins - particularly B12, B6, B9 (folate) - are all necessary for one-carbon metabolism

10.1093/ndt/gft471 Nephrol

In: Deretic V, editor

In addition, it has been shown that midbrain dopamine axons can synapse onto OLs in vivo and that some Olig2 + /PDGFR + OPCs can express Drd1/Drd2 receptors (Caldwell et al., 2023), implying that dopaminergic fibers can directly signal to OPCs, potentially influencing myelination

2.3.3 Sphingosine-1-phosphate receptor 2: potential crosstalk with conjugated bile acids in TIME Beyond receptors primarily sensing unconjugated or secondary BAs, the G protein-coupled receptor Sphingosine-1-Phosphate Receptor 2 (S1PR2) represents another signaling node potentially linking BA metabolism to the TIME, primarily through interactions with conjugated bile acids (CBAs) (103)
