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Thiazolidinediones (TZD) The TZDs, such as rosiglitazone (Avandia) and pioglitazone (Actos) have proven useful in treating the hyperglycemia associated with insulin-resistance in both type 2 diabetes and non-diabetic conditions

(PubMed) Gholizadeh M, Basafa Roodi P, Abaj F, et al

587 When topical treatments are insufficient, Botulinum Toxin Type A injections into the affected areas inhibit acetylcholine release at neuromuscular junctions, resulting in a significant reduction in sweating for several months

Regulation of energy metabolism through modulation of acyl CoA:CoA ratio Free (nonesterified) CoA is required as a cofactor for numerous cellular reactions

& Kumar, V

Meanwhile, it is still difficult to diagnose depression mainly relying on clinical phenomenology and the judgment of psychiatrists (5)