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A., Donaldson, D
examined the use of allogeneic human bone marrow mesenchymal stem cells (allo-hBM-MSCs) compared to PolyMem (PolyMem, Ferris Mfg

found disease activity in experimental anti-laminin 332 MMP using C5-deficient neonatal mice, the recent finding of nearly abrogated disease activity in another anti-laminin 332 MMP mouse model using C5aR1-deficient adult mice favors complement inhibition as treatment option in MMP [209, 210]

But concerns persist that ICS may reduce production of the steroid hormone cortisol in the body leading to adrenal suppression

PMID: 17 YanHXiaoNYangBZhangJXuYChenBet al

10.1208/s12248-014-9605-8 53 DhillonN.AggarwalB
