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A new multisociety, multispecialty position statement published in RAPM and approved by the American Society of Regional Anesthesia and Pain Medicine Board of Directors addresses this important and practical question

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Simply stacking pillows proves less effective and may create neck discomfort without achieving the same angle

Thus, it is likely to be that poor Met binding of aMD5-FLAG-mAb resulted in the unexpected capture of a background protein via nonspecific interactions