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Literature reports suggest an apparent association between use of corticosteroids and left ventricular free wall rupture after a recent myocardial infarction

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For clinical and applied practice, the most evidence-based approach is phase-aware interpretation of biomarkers (especially iron indices) and targeted screening of high-risk subgroups (e.g., heavy menstrual bleeding, athletes, obesity/PCOS), rather than routine phase-specific dosing protocols

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