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Interleukin-6 The major source of interleukin-6 (IL-6) seen in IBD has been shown to be intestinal epithelial cells and lamina propria mononuclear cells.48 Recent studies indicate the involvement of IL-6 in intestinal TJ regulation.49 IL-6 increases paracellular permeability selectively to cations, but not to macromolecules, with an increase in pore-forming claudin-2 in intestinal epithelial cells, which requires the mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) and PI3K/Akt signaling activations

Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults

Acne marks and dark spots start fading as antioxidants work overtime to repair damaged skin cells

Complex coacervation: principles, mechanisms and applications in microencapsulation

In January 2025, Novo Nordisk disclosed key findings from the STEP UP study , a Phase IIIb trial within the global STEP program