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Dimers enhance activity by linking two molecules of artemisinin, such as a 2-5-fold increase in anti-malarial activity and stronger inhibition of the PI3K/Akt pathway, which can overcome tumor resistance (Yue et al., 2023

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8.6.2 Non-mammalian eukaryotic systems 8.6.2.1 Gene mutation assays Acetaldehyde (0.1% or 1.0% for 2 h) induced mutations in genes that affect the egg-laying system of Caenorhabditis elegans (Greenwald & Horvitz, 1980)

Autologous mesenchymal stromal cells embedded in tricalcium phosphate for posterolateral spinal fusion: results of a prospective phase I/II clinical trial with long-term follow-up

19 Slowing of the epidermal turnover rate and cell cycle lengthening coincides with a slower wound healing and less effective desquamation in older adults

Increased ROS production is a consequence of prolonged endoplasmic reticulum stress and mitochondrial-derived oxidative stress in cardio-metabolic disorders