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RNA samples were reverse transcribed using the Prime Script RT Reagent Kit (Perfect Real Time, Takara Bio Inc., Shiga, Japan)

NF-B translocated into the nucleus activates the transcription of target genes (Basak and Hoffmann 2008)

Studies of SOD activity in AD have resulted in conflicting reports

Previous studies have used dual luciferase reporter gene assays to demonstrate a direct interaction between STAT3 and LDHA promoter[36], Based on this, we conducted ChIP experiments to further confirm the strong binding interaction between STAT3 and the promoter of the LDHA gene

It enhances the activity of natural killer cells, which are crucial for fighting off infections and diseases

Prevents fat accumulation by inhibiting lipogenesis, making it harder for the body to store excess fat